Detection, genotyping and phylogenesis of human papillomavirus (HPV) and Epstein-Barr virus (EBV) in patients with lung cancer

Authors

  • Łukasz Podsiadło Department of Virology, Medical University of Lublin, Poland Author
  • Sławomir Mańdziuk Department of Pneumology, Oncology and Allergology, Medical University of Lublin, Poland Author
  • Małgorzata Polz-Dacewicz Department of Virology, Medical University of Lublin, Poland Author
  • Agnieszka Stec Department of Virology, Medical University of Lublin, Poland Author
  • Jarosław Buczkowski Department of Pneumology, Oncology and Allergology, Medical University of Lublin, Poland Author

DOI:

https://doi.org/10.12923/j.2084-980X/25.2/a.10

Keywords:

lung cancer, human papillomavirus, Epstein-Barr virus, sequencing, phylogenetic tree

Abstract

The lung cancer is one of the most common cancers in humans. It is now believed, that the most common cause of this disease is smoking, nevertheless also research on oncogenic viruses participating in the development of this type of tumor confirms that. Human papillomavirus (HPV) and Epstein-Barr virus (EBV) are the etiologic agents of several types of cancer. The dynamic development of molecular biology techniques and bioinformatics allows for the genotyping of microorganisms in a more accurate and reliable way. In this paper, we carried out the detection and genotyping of HPV and EBV in fragments of fresh tissue obtained from patients with the lung cancer. In addition, typing results are presented graphically in phylogenetic trees.

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Published

2012-04-01

How to Cite

Podsiadło, Łukasz, Mańdziuk, S., Polz-Dacewicz, M., Stec, A., & Buczkowski, J. (2012). Detection, genotyping and phylogenesis of human papillomavirus (HPV) and Epstein-Barr virus (EBV) in patients with lung cancer. Current Issues in Pharmacy and Medical Sciences, 25(2), 159-163. https://doi.org/10.12923/j.2084-980X/25.2/a.10