The influence of coating on release of paracetamol from the multi-compartment systems

Authors

  • Tomasz Stawarski Department of Applied Pharmacy and Bioengineering, Faculty of Pharmacy, Medical University of Warsaw, Poland Author
  • Edmund Sieradzki Department of Applied Pharmacy and Bioengineering, Faculty of Pharmacy, Medical University of Warsaw, Poland Author
  • Beata Baran Department of Applied Pharmacy and Bioengineering, Faculty of Pharmacy, Medical University of Warsaw, Poland Author
  • Agnieszka Stawarska Department of Bromatology, Faculty of Pharmacy, Medical University of Warsaw, Poland Author

DOI:

https://doi.org/10.12923/j.2084-980X/26.2/a.09

Keywords:

multi-compartment system, modified release, minitablets, coated tablets, paracetamol

Abstract

A multi-compartment system enables modification of medicinal substance release. Nine series of multi-compartment systems were prepared, where each contained 5 minitablets. Application of different envelopes (OPADRY II WHITE and ACRYL EZE – PINK), coating the individual minitablets and complete multi-compartment systems, allowed for modeling medicinal substance release from the tested drug forms. Dissolution test of paracetamol was tested. The results were processed using the Statistica 9.0 (StatSoft, USA).

References

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Published

2013-05-01

How to Cite

Tomasz Stawarski, Sieradzki, E., Baran, B., & Stawarska, A. (2013). The influence of coating on release of paracetamol from the multi-compartment systems. Current Issues in Pharmacy and Medical Sciences, 26(2), 160-162. https://doi.org/10.12923/j.2084-980X/26.2/a.09