Vol. 22 No. 2 (2009), Artykuły
Vol. 22 No. 2 (2009)

Chemical modification of implant vascular biomaterial. Part I. Optimization of gentamicin and ciprofloxacin modificationconditions on vascular grafts to obtain antibacterial properties

Artykuły
Published 2009-06-30
Małgorzata Miazga-Karska
Department of Biochemistry, Medical University of Lublin
Grażyna Ginalska
Department of Biochemistry, Medical University of Lublin

Abstract

We worked on aminoglicosides and fluoroquinolons immobilization to gelatin-sealed vascular prostheses (made of polyethyleneterephtalate-PET-fibers) to obtain effective and prolonged antibacterial protection of implants. The optimal conditions of cyprofloksacin immobilization were determined a new types of prostheses (carrier - Ciprofloxacin and carrier - Gentamicin-Ciprofloxacin) were created.

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