Abstract
The series of new derivatives of 1H-3-arylsulfonylamino-4-amino-5-tosylimino-1,2,4-triazole was obtained by condensation of 1-arylsulfonylamino-2,3-diaminoguanidyny with dimethyl N-tosyliminodithioic acid ester.Considering the structure of the obtained compounds it can be expected that these compounds can reveal pharmacological activity.
References
1. Akhtar T., Harneed S., Shahid K.: 3-Substituted-4-amino-5-thioxo-1H,4H-1,2,4-triazoles. Medicinal Chemistry, 4(6), 539, 2008.
2. Gumrukcuoglu N., Serdar M. et al.: Synthesis and Antimicrobial Activities of Some New 1,2,4-Triazole Derivatives. Turk. J. of Chem., 31(3), 335, 2007.
3. Kaplaushenko A. G.: Structure and antimicrobial and antifungal activities of 1,2,4-triazole amino- and thioderivatives.Farm. Zh., 4, 64, 2007.
4. Kumar U., Bansal M., et al.: Synthesis of 4-amino-5-aryl-1,2,4-triazoles and screening for antibacterial activity.Int. J. of Chem.Sci., 6(1), 262, 2008.
5. Kumar U., Bansal M. et al.: Synthesis and antifungal activity of 4-amino-5-aryl-1,2,4-triazoles. Journal of Pure& Applied Microbiology, 1(2), 341, 2007.
6. Ozdemir A., Turan-Zitouni G. et al.: Synthesis of some 4-arylidenamino-4H-1,2,4-triazole-3-thiols and their antituberculosis activity. J. Enzyme Inhibition & Medicinal Chemistry, 22(4), 511, 2007.
7. Rządkowska M.: Synthesis of new derivatives of 1H-3-arylosulfonyloamino-4-amino-1,2,4-triazole. Annales UMCS, Sect. DDD, 16, 20, 165, 2003.
8. Rządkowska M.: Synthesis of new derivatives of 1H-3-arylosulfonylamino-4-amino-1,2,4-triazolin-5-one. Annales UMCS, Sect. DDD, N1, 19, 129, 2008.
9. Tumosiene I., Kantminiene K. et al.: Synthesis of Azole Derivatives from 3-Phenylaminopropanhydrazide and Evaluation of Their Antimicrobial Efficacy. Heterocycles, 78(1), 59, 2009.
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 Unported License.
Copyright (c) 2009 Author