Abstract
Symptoms of adversary drug action in the area of the oral cavity can appear both after drugs administered generally and the ones administered locally. The whole picture of allergic reactions is constituted by several clinical symptoms, some of which are difficult to distinguish from the symptoms of toxic reactions. Among local damage in the oral cavity caused by preparations used in stomatologic practice there happens to take place damage inflicted by caustic action of chemical substances, and tissue damage which is the result of congenital hypersensivity (idiosyncrasy) or acquired allergy. The presented case shows the possibility of occurrence of a violent local allergic reaction to Metronidazole ointment.
References
1. Abdollahi M., Radar M.: A review of drug-induced oral reactions. J. Contemp. Dent. Pract., 4, 1, 10, 2003.
2. Anibarro B., Fontela J. L.: Immediate rhinoconjunctivitis induced by metamizole and metronidazole. Ann. Allergy Asthma Immunol., 78, 345, 1997.
3. Madsen J. T., Thormann J., Kerre S. et al.: Allergic contact dermatitis to topical metronidazole – 3 cases. Contact Dermatitis, 56, 364, 2007.
4. Nnoruka E. N., Ikeh V. O., Mbah A. U.: Fixed drug eruption in Nigeria. Int. J. Dermatol., 45, 1062, 2006.
5. Watsky K L.: Acute generalized exanthematous pustulosis induced by metronidazole: the role of patch testing. Arch. Dermatol., 135, 93, 1999.

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