Orosomucoid on the surface and inside the leukocytes in myocardial infarction

Authors

  • Oleksandr Brazaluk Dnipropetrovsk State Medical Academy, Department of Biochemistry, Medical and Pharmaceutical Chemistry, Ukraine Author
  • Anna Maslak Dnipropetrovsk State Medical Academy, Department of Biochemistry, Medical and Pharmaceutical Chemistry, Ukraine Author
  • Ivan Mashejko Dnipropetrovsk State Medical Academy, Department of Biochemistry, Medical and Pharmaceutical Chemistry, Ukraine Author
  • Olena Koval Dnipropetrovsk State Medical Academy, Department of Biochemistry, Medical and Pharmaceutical Chemistry, Ukraine Author
  • Oleksandr Minchenko Dnipropetrovsk State Medical Academy, Department of Biochemistry, Medical and Pharmaceutical Chemistry, Ukraine Author

Keywords:

orosomucoid, leukocyte, myocardial infarction, flow cytometry

Abstract

We investigated the concentration  and distribution of ORM in blood cells of 12 patients collected at the first day after the heart attack. We showed that the level of  ORM was increased 1.27 times in the serum in myocardial infarction. The ORM distribution on the surface and inside the blood cells is a more informative marker and can be successfully used as additional criteria for monitoring patients with acute coronary syndromes.

References

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5. Poland D.C.W. et al.: Activated human PMN synthesize and release a strongly fucosylated glycoform of alpha-1-acid glycoprotein, which is transiently deposited in human myocardial infarction Journal of Leukocyte Biology., 78, 453, 2005

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Published

2010-12-30

Issue

Vol. 23 No. 4 (2010): Annales UMCS, Pharmacia, Sectio DDD, Volume XXIII

Section

Artykuły

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Copyright (c) 2010 Authors

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This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 Unported License.