Keywords
breast cancer
breast
malignancy
neoplasm
Abstract
The paper aims to introduce the case of an extensive breast malignancy – phyllodes tumor. This type of breast neoplasm is relatively rare. Indeed, it accounts for only 0.3-1% of all breast malignant tumours. In the paper, patient, disease, and treatment methods were described and evaluated. The efficacy of surgical treatment and adjuvant therapy (radiotherapy and chemotherapy) was assessed based on literature data. The authors concluded that late diagnosis of phyllodes tumor causes the necessity of mastectomy and radiotherapy and aggravates the prognosis.References
1. Guerrero MA, Ballard BR, Grau AM. Malignant phyllodes tumor of the breast: review of the literature and case report of stromal overgrowth. Surg Oncol. 2003;12.1:27-37.
2. Zhou ZR, Wang CC, Yang ZZ, Yu XL, Guo XM. Phyllodes tumors of the breast: diagnosis, treatment and prognostic factors related to recurrence. J Thorac Dis. 2016;8(11):3361.
3. Tavassoli FA, Deville P. Pathology and genetics of tumours of the breast and female genital organs. WHO Classification of Tumours series – volume IV. Lyon, France: IARC Press; 2003.
4. Muller J. Über den feinern Bau und die Formen der krankhaften Geschwülste: in zwei Lieferungen. Berlin: G Reimer. 1838:54-7.
5. Moffat CJ, Pinder SE, Dixon AR, Elston CW, Blamey RW, Ellis IO. Phyllodes tumour of the breast: a clinicopathological review of the thirty-two cases. Histopathology. 1995,27.3:205-18.
6. Parker SJ, Harries SA. Phyllodes tumours. Postgrad Med J. 2001;77:428-35.
7. Ramakant P, Chakravarthy S, Cherian JA, Abraham DT, Paul MJ. Challenges in management of phyllodes tumors of the breast: a retrospective analysis of 150 patients. Indian J Cancer. 2013;50(4):345-8.
8. Macdonald OK, Lee CM, Tward JD, Chappel CD, Gaffney DK. Malignant phyllodes tumor of the female breast. Cancer. 2006;107(9):2127-33.
9. Hines JR, Murad TM, Beal JM. Prognostic indicators in cystosarcoma phylloides. Am J Surg. 1987;153(3):276-80.
10. Wang Y. Development of cancer diagnostics –from biomarkers to clinical tests. Transl Cancer Res. 2015;4(3):270-9.
11. Sotheran W, Domjan J, Jeffrey M, Wise MH, Perry PM. Phyllodes tumours of the breast-a retrospective study from 1982-2000 of 50 cases in Portsmouth. Ann R Coll Surg Engl. 2005;87(4):339-44.
12. Haberer S, Laé M, Seegers V, Pierga JY, Salmon R, Kirova YM, et al. Management of malignant phyllodes tumors of the breast: the experience of the Institut Curie. Cancer Radiother. 2009;13(4):305-12.
13. Morales-Vásquez F, Gonzalez-Angulo AM, Broglio K, Lopez‐Basave HN, Gallardo D, Hortobagyi GN, et al. Adjuvant chemotherapy with doxorubicin and dacarbazine has no effect in recurrence-free survival of malignant phyllodes tumors of the breast. Breast J. 2007;13(6):551-6.
14. Belkacémi Y, Bousquet G, Marsiglia H, Ray-Coquard I, Magné N, Malard Y. et al. Phyllodes tumor of the breast. Int J Radiat Oncol Biol Phys. 2008;70(2):492-500.
15. Pandey M, Mathew A, Abraham EK, Rajan B. Primary sarcoma of the breast. J Surg Oncol. 2004;87(3):121-5.
16. Gnerlich JL, Williams RT, Yao K, Jaskowiak N, Kulkarni SA. Utilization of radiotherapy for malignant phyllodes tumors: analysis of the National Cancer Data Base, 1998-2009. Ann Surg Oncol. 2014; 21(4):1222-30.
17. Nowecki Z, Jeziorski A. Chirurgiczne leczenie zmian nowotworowych piersi: II konsensus PTChO. Gdańsk: Via Medica; 2019:63-64.
18. Guerrero, Marlon A., Billy R. Ballard, and Ana M. Grau. Malignant phyllodes tumor of the breast: review of the literature and case report of stromal overgrowth. Surg Oncol. 2003;12(1):27-37.
19. Belkacémi Y, Bousquet G, Marsiglia H, Ray-Coquard I, Magne N, Malard Y, et al. Phyllodes tumor of the breast. Int J Radiat Oncol. 2008;70(2):492-500.
20. Kapiris I, Nasiri N, Healy V, Gui GPH. Outcome and predictive factors of local recurrence and distant metastases following primary surgical treatment of high-grade malignant phyllodes tumours of the breast. Eur J Surg Oncol. 2001;27(8):723-30.
21. Khosravi-Shahi P. Management of non metastatic phyllodes tumors of the breast: review of the literature. Surg Oncol. 2011; 20(4):e143-e148.
22. Chen WH, Cheng SP, Tzen CY, Yang TL, Jeng KS, Liu CL, Liu TP. Surgical treatment of phyllodes tumors of the breast: retrospective review of 172 cases. J Surg Oncol. 2005;91(3):185-94.
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 Unported License.
Copyright (c) 2021 Authors