Keywords
еxpert evaluation
Abstract
On the basis of results of experimental evaluation by 88 doctors and 100 pharmacists, the availability of information for them on probiotics has been investigated; new sources of such information have been detected, experts’ attitude to new probiotics has been studied. In the course of administration or recommendation of probiotics, experts are, mainly, guided by standards of medical aid and by their own experience. The main favorable effects of probiotics on human organism, in respondents’ opinion, are the normalization of the content of intestinal microflora and the normalization of functioning of digestive tract of human, as well as antialergetic and immunomodeling action. It is found that the main indication for application of probiotics are the syndrome of irritation of intestine and associated with antibiotic diarrhea. The averaged estimation (in points) of medicines has been calculated according to the following parameters: effectiveness, safety, frequency of prescription. With this, the competence of the experts was taken into account. The results of the carried out experts’ estimation can be used for optimization of the system of choice of probioticsReferences
1. Mechnykov II. Etiudy optymizmu. Moskva: Nauka, 1988: 164-165. Available at: http://www.klex.ru/5by.
2. Lilly DM, Stillwell RH. Probiotics: growth-promoting factors produced by microorganisms. Science. 1965;147(3659):747-8.
3. Fuller R. Probiotics in man and animals. J Appl Bacteriol. 1989;66(5):365-78.
4. Parker RB. Probiotics, the other half of the antibiotic story. Anim. Nutr. Health. 1974;29:4-8.
5. Guarner F, Sanders M-E, Eliakim R, Fedorak R, Gangl A, Garisch J et al. WGO Global Guideline. Probiotics and prebiotics. Available at: http://www.worldgastroenterology.org/guidelines/global-guidelines/probiotics-and-prebiotics/probiotics-and-prebiotics-english.
6. Goldenberg JZ, Lytvyn L, Steurich J, Parkin P, Mahant S, Johnston BC. Probiotics for the prevention of pediatric antibiotic-associated diarrhea. Cochrane Database of Syst. Rev. 2015:12. Available at: http://www.cochrane.org/CD004827/IBD_probiotics-prevention-antibiotic-associated-diarrhea-children.
7. Naidoo K, Gordon M, Fagbemi AO, Thomas AG, Akobeng AK. Probiotics for maintenance of remission in ulcerative colitis. Cochrane Database of Syst. Rev. 2011:12. Available at: http://www.cochrane.org/CD007443/IBD_probiotics-for-maintenance-of-remission-in-ulcerative-colitis.
8. Senok AC, Verstraelen H, Temmerman M, Botta GA .Probiotics for the treatment of bacterial vaginosis. Cochrane Database of Syst. Rev. 2009:4. Available at: http://www.cochrane.org/CD006289/STI_probiotics-for-the-treatment-of-bacterial-vaginosis.
9. Boyle RJ, Bath-Hextall FJ, Leonardi-Bee J, Murrell DF, Tang MLK. Probiotics for treating eczema. Cochrane Database of Syst. Rev.2008;4. Available at: http://www.cochrane.org/CD006135/SKIN_probiotics-for-treating-eczema.
10. Chalas R, Janczarek М, Bachanek Т, Mazur Е, Cieszko-Buk М, Szymanska J. Characteristics of oral probiotics – a review. Curr. Issues Pharm. Med. Sci. 2015;29: 8-10.
11. The technique of complex estimation of medicines basing on the example non-steroidal anti-inflammatory medicines for treatment of rheumatoid arthritis/ Methodical recomendational/ N.L.Herbolka, O.L.Hrom, Danylo Halytsky Lviv National Medical University. – Kyiv, 2008. –21 p.
12. Gutiérrez-Castrellón P, Indrio F, Bolio-Galvis A, Jiménez-Gutiérrez C, Jimenez-Escobar I, López-Velázquez G. Efficacy of Lactobacillus reuteri DSM 17938 for infantile colic: Systematic review with network meta-analysis. Medicine (Baltimore). 2017 Dec;96(51):e9375. doi: 10.1097/MD.0000000000009375. - Available at: https://www.ncbi.nlm.nih.gov/pubmed/29390535.
13. Association of neonatologists of Ukraine. - Available at: http://old.neonatology.org.ua/uk/.
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 Unported License.
Copyright (c) 2018 Authors