Vol. 28 No. 3 (2015), Artykuły
Vol. 28 No. 3 (2015)

Xanthogranulomatous urethritis and cystitis: a rare clinical and pathological entity

Artykuły
Published 2015-11-26
Dorota Lewkowicz
Department of Clinical Pathology, Medical University of Lublin, Jaczewski 8, 20-090 Lublin, Poland
Lech Wronecki
Department of Clinical Pathology, Medical University of Lublin, Jaczewski 8, 20-090 Lublin, Poland
Iwona Pasnik
Department of Clinical Pathology, Medical University of Lublin, Jaczewski 8, 20-090 Lublin, Poland
Waldemar Bialek
Department of Urology, 1st Military Hospital, Racławickie 23, 20-904 Lublin, Poland
Beata Walczyna
Department of Clinical Pathology, Medical University of Lublin, Jaczewski 8, 20-090 Lublin, Poland
Agnieszka Fronczek
Department of Clinical Pathology, Medical University of Lublin, Jaczewski 8, 20-090 Lublin, Poland
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Keywords

xanthogranulomatous cystitis
xanthogranulomatous urethritis

Abstract

Xanthogranulomatous inflammation of the urethra and the urinary bladder is a very rare pathological condition characterized by a chronic inflammatory infiltration composed mainly of foamy macrophages, with the presence of multinucleated giant cells. In a clinical examination, it can mimic urinary bladder carcinoma. This report presents the extremely rare case of a co-existing xanthogranulomatous urethritis and cystitis in a 64-year-old woman with recurrent dysuria, and with the suspicion of malignancy - as indicated on the basis of a cystoscopic examination. The standard treatment of this disorder is surgical resection, but in the presented case, only a diagnostic biopsy was performed. Because of the persistence of clinical symptoms, a cystoscopic examination and biopsy was repeated three times in a two year period. There was no malignancy seen in the repeated biopsies.

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References

1. Ali A.M. et al.: Extensive xanthogranulomatous cystitis mimicking bladder cancer. Urol. Ann., 6, 373, 2014.

2. Bates A.W., Fegan A.W., Baithun S.I.: Xanthogranulomatous cystitis associated with malignant neoplasms of the bladder. Histopathology, 33, 212, 1998.

3. Chung D.E. et al.: Xanthogranulomatous cystitis associated with inflammatory bowel disease. Can. Urol. Assoc. J., 4, E91, 2010.

4. Chung M.K. et al.: Xanthogranulomatous cystitis associated with suture material. J Urol., 159, 981, 1998.

5. Fornari A. et al.: A case of xanthogranulomatous cystitis. Int. Urogynecol. J., 18, 1233, 2007.

6. Goel R. et al.: Xanthogranulomatous cystitis. Int. Urol. Nephrol., 39, 477, 2007.

7. Hayashi N. et al.: Xanthogranulomatous cystitis. Int. J. Urol., 10, 498, 2003.

8. http://pathologyoutlines.com/topic/bladderxanthogranulomatous.html (last access: 10.05.2015)

9. Ichikara T., Nishiura T., Kumamoto Y.: Report on two cases of the xanthogranuloma associated with urachal adenoma. Jpn. J. Urol., 53, 34, 1962.

10. Itano N.B. et al.: Xanthogranulomatous urethritis: a case report. J. Pelvic Med. Surg., 6, 284, 2000.

11. Pottakkat B. et al.: Ampullary xanthogranulomatous inflammation mimicking periampullary cancer: report of a case. J. Pancreas, 7, 222, 2006.

12. Szalat R. et al.: Physiopathology of necrobiotic xanthogranuloma with monoclonal gammopathy. J. Intern. Med., 276, 269, 2014.

13. Tai H.L., Chen C.C., Yeh K.T.: Xanthogranulomatous cystitis associated with anaerobic bacterial infection. J. Urol. 162, 795, 1999.

14. Wassiljew A. I.: Uber Erkrankugen des urachus. Z. Urol. Chir., 35,199, 1932.

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