Keywords
ointment
gel
cream
rheology
thixotropy
Abstract
The aim of the study was preparing the skin formulations with ibuprofen as ointments, creams and gels. They have been prepared by two methods; melting the components and then mixing (method 1) and in the unqutor (method 2). The preparations have been tested rheologically and determined for the consistency, pH and spreadability ex tempore and after 3 months of storage at 4° C. The studies showed that the consistency is stable during all the time of storage. The pH values were within the tolerance of the skin. The formulations prepared in the unquator have better consistency, spreadability and lower viscosity.
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