Comparison of the physical properties of ointments, creams and gels with ibuprofen obtained with two different methods according to the own compositions

Autor

  • Maria Zuń Chair and Department of Applied Pharmacy Faculty of Pharmacy, Medical University in Lublin, Poland Autor
  • Dorota Dwornicka Chair and Department of Applied Pharmacy Faculty of Pharmacy, Medical University in Lublin, Poland Autor
  • Katarzyna Świąder Chair and Department of Applied Pharmacy Faculty of Pharmacy, Medical University in Lublin, Poland Autor
  • Katarzyna Wojciechowska Chair and Department of Applied Pharmacy Faculty of Pharmacy, Medical University in Lublin, Poland Autor
  • Łukasz Zimmer Chair and Department of Applied Pharmacy Faculty of Pharmacy, Medical University in Lublin, Poland Autor
  • Agata Dziekańska Chair and Department of Applied Pharmacy Faculty of Pharmacy, Medical University in Lublin, Poland Autor
  • Ewa Poleszak Chair and Department of Applied Pharmacy Faculty of Pharmacy, Medical University in Lublin, Poland Autor

DOI:

https://doi.org/10.12923/j.2084-980X/25.4/a.09

Słowa kluczowe:

ibuprofen, ointment, gel, cream, rheology, thixotropy

Abstrakt

The aim of the study was preparing the skin formulations with ibuprofen as ointments, creams and gels. They have been prepared by two methods; melting the components and then mixing (method 1) and in the unqutor (method 2). The preparations have been tested rheologically and determined for the consistency, pH and spreadability ex tempore and after 3 months of storage at 4° C. The studies showed that the consistency is stable during all the time of storage. The pH values were within the tolerance of the skin. The formulations prepared in the unquator have better consistency, spreadability and lower viscosity.

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Opublikowane

2012-12-28

Jak cytować

Zuń, M., Dwornicka, D., Świąder, K., Wojciechowska, K., Zimmer, Łukasz, Dziekańska, A., & Poleszak, E. (2012). Comparison of the physical properties of ointments, creams and gels with ibuprofen obtained with two different methods according to the own compositions. Current Issues in Pharmacy and Medical Sciences, 25(4), 384-387. https://doi.org/10.12923/j.2084-980X/25.4/a.09