Abstract
The nomenclature of auxiliary substances which are used in the technology of medicinal preparations depending on the method of application of preparation and the dosage form is presented. The choice of auxiliary substances on the basis of literature information on biochemical researches is justified. An example of determining the composition of solutions for peritoneal dialysis on the basis of of acid-base equilibrium indexes and electrolyte balance of organism is given.
References
1. Chan T. M. et al.: Studying the effects of new peritoneal dialysis solutions on the peritoneum. Perit. Dial. Int., 27, 87, 2007.
2. Drug actions:basic principles and therapeutic aspects /Ernst Mutschler et al., 1995.
3. Europian Pharmacopoeia. 4th ed., 2003.
4. Nastanova 42-3.1:2004 Nastanovy z jakosti. Likarski zasobu. Pharmaceutychna rozrobka. MOZ Ukrainy, 2004.
5. Nastanova 42-3.6:2004 Nastanovy z jakosti. Likarski zasobu. Dopomirzni rechovyny. MOZ Ukrainy, 2004.
6. Patent EP 1 166 787 A2, A61K 33/10. Stable amino acid based bicarbonate solutions for peritoneal dialysis and hemodialysis /Yatzidis (GR), 01600017.6, 02.01.2002.
7. Patent EP 804931 B1, A61K 45/06. Peritoneal dialysis solutions and their use to minimize injury to mesothelial cells /Breborowich Andrzej (PL) et al., 97201673.7, 07.05.2003.
8. Patent EP WO 96/01118, A61K 33/14. Biochemically balanced peritoneal dialysis solutions/Martis Leo et al., PCT/US95/06784, 18.01.1996.
9. Sastry S. V. et al.: Recent technological advances in oral drug delivery – a review. PSTT, 3, 4, 138, 2000.
10. Technologia i standartizacia lekarstv. Sbornik Nauchnych Trudov. T 2, 2000.
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 Unported License.
Copyright (c) 2009 Authors