Abstract
The Aloë genus has been used for thousands of years in the treatment of burns, wounds, skin irritations and constipation. Aloe has a broad range of pharmacological properties, including antiinfl ammatory, antiviral, antioxidative actions, antibacterial, immunostimulant, antifungal, analgesic, antitumor, antidiabetic and inhibition of tumor cells activation and proliferation. Phenolic acids are active compounds and may exert a beneficial impact on the pharmacological activity of Aloë. Thus, TLC and HPLC methods were used for quantitative and qualitative evaluation of phenolic acids, both free and liberated (by acidic and alkaline hydrolysis) in the leaves of Aloë arborescens and other Aloë species. The assay demonstrated the presence of phenolic acids mainly: p-coumaric and ferulic in the material. The leaves of A. arborescens also contain 11 other phenolic acids: homoprotocatechuic, β-phenyllactic, protocatechuic, caffeic, p-hydroxybenzoic, p-hydroxyphenylacetic, syringic, o-hydroxyphenylacetic, trans-cinnamic and vanillic. The content of particular compounds was demonstrated and it ranged from 0.01 mg % (protocatechuic acid, free) to 1.46 mg % (p-coumaric acid cis, liberated after alkaline hydrolysis), in the fresh material and, respectively, 0.26 mg % to 41.81 mg % of dry plant material.
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