Vol. 22 No. 4 (2009), Artykuły
Vol. 22 No. 4 (2009)

Activity of anidulafungin against Candida albicans isolated from clinical specimens

Artykuły
Published 2009-12-30
Anna Biernasiuk
Department of Pharmaceutical Microbiology, Medical University of Lublin
Katarzyna Matuska
Department of Medical Microbiology, Clinical Hospital No. 1 in Lublin
Agnieszka Grzegorczyk
Department of Pharmaceutical Microbiology, Medical University of Lublin
Justyna Szymańska
Department of Pharmaceutical Microbiology, Medical University of Lublin
Anna Malm
Department of Pharmaceutical Microbiology, Medical University of Lublin, Department of Medical Microbiology, Clinical Hospital No. 1 in Lublin

Abstract

Infections caused by C. albicans are an important medical problem in people from risk groups, e.g. hospitalized patients. The aim of this paper was to analyse by the E-test procedure, the in vitro activity of anidulafungin against clinical isolates of C. albicans. This antifungal agent belongs to new class of echinocandins. The data presented in this paper indicate that all isolates of C. albicans from various clinical specimens were susceptible to anidulafungin. Our data and those from the literature confirm the validity of including anidulafungin for the list of drugs effective in the therapy of infections caused by C. albicans. Morever, the E-test procedure may be used routinely for determination of sensitivity of Candida spp. to anidulafungin.

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