Comparison of colonization of the upper respiratory tract by Haemophilus influenzae and Staphylococcus aureus in healthy pre-school children exposed and unexposed to tobacco smoke
DOI:
https://doi.org/10.12923/Keywords:
influenzae, Staphylococcus aureus, upper airways colonization, passive smoking, healthy pre-school childrenAbstract
The effect of tobacco smoke exposure on colonization of the upper respiratory tract by Haemophilus influenzae and Staphylococcus aureus was assessed in healthy pre-school children (3-5 years old). A total of 344 children, including 268 attending day care center and 76 staying at home were assayed. For identification of the bacterial isolates, routine diagnostic methods were used. The exposure to tobacco smoke statistically significantly increased the colonization of the upper respiratory tract by H. influenzae, but not by S. aureus. The rate of H. influenzae colonization in exposed and unexposed children in total population was 16.3% vs. 7.0% (p = 0.0098, RR = 2.327) and in children attending day care centers - 17.2% vs. 7.1% (p = 0.014, RR = 2.41). The obtained data suggest that in young children, especially those attending day care centers, passive smoking may predispose to colonization of the upper airways by H. influenzae.
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