Experimental correction of pathological changes in salivary glands by multiprobiotic Symbiter® acidofilus under conditions of hypergastrinemia

Authors

  • Andriy Sukhomlyn Ukrainian Medical Stomatological Academy, Biochemistry Department, Poltava, Ukraine Author
  • Karine Neporada  Ukrainian Medical Stomatological Academy, Biochemistry Department, Poltava, Ukraine Author

DOI:

https://doi.org/10.12923/

Keywords:

salivary glands, omeprazole, hypergastrinemia, polyamines, NO-ergic systems, Symbiter ® Acidophilus

Abstract

Under conditions of long omeprazole introduction pathological changes in salivary glands tissues appear: intensification of free-radical oxidation, disbalance of proteolysis by decompensated type, increased activity of б-amilase, disbalance of polyamines and NO-ergic systems. Experimental correction by multiprobiotic Symbiter ® Acidophilus promotes normalisation of pathological changes in salivary glands of rats during long introduction of proton pomp inhibitor because free-radical oxidation and proteolytic processes are depressed, normalises balance of the polyamines and NO-ergic systems.

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Published

2010-09-30

Issue

Vol. 23 No. 3 (2010): Annales UMCS, Pharmacia, Sectio DDD, Volume XXIII

Section

Artykuły

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