Effect of pro-inflammatory cytokine-mediated mechanism on quality of gastrointestinal restitutio ad integrum

Authors

  • Nazar Hrytsevych Danylo Halytskyi Lviv National Medical University, Physiology Department, Ukraine Author
  • Maryana Zvir Danylo Halytskyi Lviv National Medical University, Physiology Department, Ukraine Author
  • Oksana Zayachkivska Danylo Halytskyi Lviv National Medical University, Physiology Department, Ukraine Author
  • Mechyslav Gzhgotskyi Danylo Halytskyi Lviv National Medical University, Physiology Department, Ukraine Author

DOI:

https://doi.org/10.12923/

Keywords:

esophageal mucosa, melatonin, ulcer

Abstract

We studied the morphofunctional changes in esophageal mucosa after  the experimental injury by acid-pepsin perfusion and stress inducted injury with and without melatonin treatment. Melatonin-treatment enhanced epithelial proliferation and accelerated the healing activity of the esophageus tissue. Melatonin, a perspective and potent anti-inflammatory agent, can be used with antiulceric and healing scope.

References

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Published

2010-09-30

Issue

Vol. 23 No. 3 (2010): Annales UMCS, Pharmacia, Sectio DDD, Volume XXIII

Section

Artykuły

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