Effects of Bergenia crassifolia lyophilized water extract on carbon tetrachloride-induced chronic liver injury in rats

Authors

  • Igor Benzel Danylo Halytskyi Lviv National Medical University, Pharmacognosy Department, Pharmacology Department, Pathomorphology Department, Ukraine Author
  • Iryna Havrylyuk Danylo Halytskyi Lviv National Medical University, Pharmacognosy Department, Pharmacology Department, Pathomorphology Department, Ukraine Author
  • Olena Gavrilyuk Danylo Halytskyi Lviv National Medical University, Pharmacognosy Department, Pharmacology Department, Pathomorphology Department, Ukraine Author
  • Igor Nektjegajev Danylo Halytskyi Lviv National Medical University, Pharmacognosy Department, Pharmacology Department, Pathomorphology Department, Ukraine Author

DOI:

https://doi.org/10.12923/

Keywords:

Bergenia crassifolia, hepatic fibrosis, carbon tetrachloride

Abstract

BCLWE exerts a hepatoprotective effect against chronic CCl4-induced lesions of liver tissue in rats, which is confirmed by prevention of serum ALT and AST activity elevation and progression of liver cell injury and fibrosis.

References

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4. Goel R.K., Maiti R.N., Manicckam A.: Antiulcer ativity of naturally occurring pyrano-coumarin and isocoumarins and their effect on prostanoid synthesis using human colonic mucosa. Indian J. Exp. Biol., 35, 1080, 1997.

5. Lim H.K., Kim H.S., Choi H.S., Choi J.W.: Protective and therapeutic effects of MCWE on carbon tetrachloride- and galactosamine-induced hepatotoxiciry in rats. J. Appl. Pharmacol., 7, 35, 1999.

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Published

2010-09-30

Issue

Vol. 23 No. 3 (2010): Annales UMCS, Pharmacia, Sectio DDD, Volume XXIII

Section

Artykuły

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