Essential oil from fruits of Angelica officinalis and its antibacterial activity

Authors

  • Krystyna Skalicka-Woźniak Department of Pharmacognosy with Medicinal Plant Laboratory, Medical University of Lublin, Poland Author https://orcid.org/0000-0002-9313-5929
  • Renata Łoś Department of Pharmaceutical Microbiology, Medical University of Lublin, Poland Author
  • Zofia Ulz Main Pharmaceutical Inspectorate, Warsaw, Poland Author
  • Kazimierz Głowniak Department of Pharmacognosy with Medicinal Plant Laboratory, Medical University of Lublin, Poland Author
  • Anna Malm Department of Pharmaceutical Microbiology, Medical University of Lublin, Poland Author https://orcid.org/0000-0003-1503-7634

Keywords:

Angelica officinalis, essential oil, antibacterial activity, GC-MS

Abstract

The essential oil from the fruits of Angelica officinalis, collected in the botanical garden in Poland, was obtained by hydrodistillation (HD) techniques and analyzed using GC-MS. A total of 30 components were identified. The most abundant compound was β-phellandrene (73%). The minimal inhibitory concentration of essentials oil, defined as the lowest concentration able to inhibit visible microbial growth, and the minimal bactericidal concentration, the lowest concentration required to kill of the bacteria, were determined using the broth microdilution method and plating on agar. Essential oil showed moderate antibacterial activity against all reference strains. There was only a small difference between power of activity against Gram-positive and Gram-negative bacteria with MICs ranging from 0.62 to 1.25 mg/ml and 1.25 to 2.5 mg/ml, respectively.

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Annales Sectio DDD, XXIV, 1

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Published

2025-04-18

Issue

Vol. 24 No. 1 (2011): Annales UMCS, Pharmacia, Sectio DDD, Volume XXIV

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