A study of Na, K - ATPase and arginase activity in peripheral blood lymphocytes in patients with rheumatic diseases

Authors

  • Nataliya Lychkovska Department of Medical Biology, Parasitology and Genetics, Ukraine Author
  • Roman Fafula Department of Medical Biology, Parasitology and Genetics, Ukraine Author
  • Ulyana Efremova Department of Medical Biology, Parasitology and Genetics, Ukraine Author
  • Zinoviy Vorobers Department of Medical Biology, Parasitology and Genetics, Ukraine Author

Keywords:

Na+, K+-ATPase, arginase, rheumatoid arthritis, spondyloarthritits, lymphocytes

Abstract

The changes of Na+, K+-ATPase and arginase enzyme activity of peripheral blood lymphocytes in patients with a rheumatoid arthritis and spondyloarthritis have been studied. It was shown the significant decrease of ouabain-sensitive Na+, K+-ATPase enzyme activity in patients with rheumatic diseases in comparison to the practically healthy donors. Also we demonstrated the significant increase of arginase enzyme activity in patients with rheumatic diseases in comparison to the practically healthy donors. The dynamics of Na+, K+-ATPase and arginase enzyme activity changes is observed after patient’s treatment in hospital.

References

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Annales Sectio DDD, XXIV, 1

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Published

2025-04-18

Issue

Vol. 24 No. 1 (2011): Annales UMCS, Pharmacia, Sectio DDD, Volume XXIV

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Artykuły

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