FAPA mass spectrometry of hydroxychalcones. Comparative studies with classical methods of ionization

Authors

  • Marek Smoluch AGH University of Science and Technology, Department of Biochemistry and Neurobiology, Faculty of Materials Science and Ceramics, Mickiewicza 30, 30-059 Cracow, Poland Author
  • Grazyna Bartkowiak Adam Mickiewicz University in Poznań, Faculty of Chemistry, Umultowska 89b, 61-614 Poznan, Poland Author
  • Edward Reszke ERTEC-Poland, Rogowska 146/5, 54-440 Wroclaw, Poland Author
  • Wojciech Lechowicz Institute of Forensic Research, Westerplatte 9, 31-033 Cracow, Poland Author
  • Jerzy Silberring AGH University of Science and Technology, Department of Biochemistry and Neurobiology, Faculty of Materials Science and Ceramics, Mickiewicza 30, 30-059 Cracow, Poland / Centre of Polymer and Carbon Materials, Polish Academy of Sciences, Curie-Sklodowskiej 34, 41-819 Zabrze, Poland Author
  • Grzegorz Schroeder Adam Mickiewicz University in Poznań, Faculty of Chemistry, Umultowska 89b, 61-614 Poznan, Poland Author

DOI:

https://doi.org/10.2478/cipms-2014-0008

Keywords:

mass spectrometry, hydroxychalcones, FAPA

Abstract

In this paper we are focused on analysis of hydroxychalcones, i.e. 2’ –hydroxychalcone, 3’ –hydroxychalcone and 4’ –hydroxychalcone, by the Flowing Atmospheric Pressure Afterglow mass spectrometry (FAPA-MS), and on comparison of the obtained data with other classical methods including ESI-MS, APCI, MALDI, and GC/EI-MS. The paper is presenting fragmentation pathways of both positive-, and negative hydroxychalcone ions. Tested compounds were characterized by comparison of the results (signals m/z and relative intensities) from the five mass spectrometry techniques, showing very good utility of FAPA method for fast and easy analysis of the low molecular weight compounds. Moreover, FAPA does not require a time-consuming derivatization, nor search for a suitable solvent or matrix, often incompatible with various ion sources. 

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Published

2014-05-30

Issue

Vol. 27 No. 1 (2014): Current Issues of Pharmacy and Medical Sciences

Section

Artykuły

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