Abstrakt
The IFN production by rat spleen lymphocytes was shown to increase by 2.5 times in comparison to control against a background of hypoacidity evoked by 28-days of OM treatment (14 mg/kg). The activity of IFN-induced enzyme 2',5'-OAS declined by 16 % in these cells. The simultaneous administration of multiprobiotic SYM and OM resulted in IFN titer increase in comparison to hypoacidic animals. The 2',5'-OAS activity in spleenocytes didn’t change. SYM displayed interferonogenic properties via gastric microflora normalization and suppressing inflammation.
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