Interakcje miedzy nikotyną i morfiną w modelach zwierzęcych
DOI:
https://doi.org/10.2478/v10080-008-0182-yAbstrakt
Morfina i nikotyna są jednymi z najczęściej nadużywanych środków psychoaktywnych u ludzi, wywołujących silne uzależnienie psychofi zyczne. Wiele danych literatury wskazuje na istnienie funkcjonalnych interakcji miedzy tymi związkami, co świadczy o współdziałaniu układu opioidowego i cholinergicznego. W pracy zebrano informacje dotyczące tego typu interakcji między nikotyną a morfiną w podstawowych zwierzęcych modelach doświadczalnych, ze szczególnym uwzględnieniem antynocycepcji i działań nagradzających.
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