Risk factors of the depressive and anxiety disorders development amongpatients with Adolescent Idiopathic Scoliosis and possible therapeuticinterventions

Authors

DOI:

https://doi.org/10.12923/2353-8627/2024-0009

Keywords:

depression, risk factors, anxiety, adolescent idiopathic scoliosis, mental health

Abstract

Introduction: Adolescent idiopathic scoliosis is a common type of scoliosis among adolescents. A significant problem is the coexistence of depressive and anxiety disorders. However, the causes of this condition are not fully recognized. Thus, it seems reasonable to search for possible risk factors that may trigger mental disorder occurrence.

Material and methods: This is a literature narrative review concentrating on the influence of the adolescent idiopathic scoliosis on the development of depression and anxiety disorders among adolescents, as well as possible therapeutic interventions. Google Scholar, Medline, PubMed and Science Direct databases were searched throughout January 2024 for relevant original and review
articles from 2000 to 2024, using the following keywords: “adolescent idiopathic scoliosis”, “anxiety”, “body image”, “bracing”, “chronic disease”, “depression”, “mental disorders”, “pain”, “peer relationship”, “physical activity”, “pulmonary function”, “sleep disorders”, “surgery”, “treatment”. Manuscripts in other language than Polish or English were excluded from the search. To ensure the appropriate quality of this review, the Scale for the Assessment of Narrative Review Articles was used.

Results: Chronic pain, sleep disorders, pulmonary function impairment, perception of the disease as a chronic somatic disease, disturbed body image, lack of social interactions, physical activity limitation and applied methods of treatment may lead to the depressive and anxiety disorders development in the adolescent idiopathic scoliosis course.

Conclusions: Biological and psychosocial factors contribute to the pathogenesis of depressive and anxiety disorders among patients with adolescent idiopathic scoliosis. Their identification should help create a comprehensive plan of treatment, which may effectively maximize therapeutic outcomes in the context of both scoliosis and mental disorders.

References

1. Negrini S, Donzelli S, Aulisa AG, Czaprowski D, Schreiber S, de Mauroy JC, et al. 2016 SOSORT guidelines: orthopaedic and rehabilitation treatment of idiopathic scoliosis during growth. Scoliosis Spinal Disord. 2018; 13(1): 3. Review match

2. Sung S, Chae HW, Lee HS, Kim S, Kwon JW, Lee SB, et al. Incidence and Surgery Rate of Idiopathic Scoliosis: A Nationwide Database Study. Int J Environ Res Public Health. 2021; 18(15): 8152. Review match

3. Thomas JJ, Stans AA, Milbrandt TA, Kremers HM, Shaughnessy WJ, Larson AN. Trends in Incidence of Adolescent Idiopathic Scoliosis: A Modern US Population-based Study. J Pediatr Orthop. 2021; 41(6): 327-332. Review match

4. AlNouri M, Wada K, Kumagai G, Asari T, Nitobe Y, Morishima T, et al. Diseases and comorbidities associated with early-onset scoliosis: a retrospective multicenter analysis. Spine Deform. 2023; 11(2):481-486. Review match

5. Sanders AE, Andras LM, Iantorno SE, Hamilton A, Choi PD, Skaggs DL. Clinically Significant Psychological and Emotional Distress in 32% of Adolescent Idiopathic Scoliosis Patients. Spine Deform. 2018; 6(4): 435-440. Review match

6. Mitsiaki I, Thirios A, Panagouli E, Bacopoulou F, Pasparakis D, Psaltopoulou T, et al. Adolescent Idiopathic Scoliosis and Mental Health Disorders: A Narrative Review of the Literature. Children (Basel). 2022; 9(5): 597. Review match

7. Baird C, Gardner A. A report of the number of adolescents screened as warranting further investigation for depression and social anxiety in a pre-operative cohort with idiopathic scoliosis. Surgeon. 2021; 19(5): 263-267. Review match

8. Silva SA, Silva SU, Ronca DB, Gonçalves VSS, Dutra ES, Carvalho KMB. Common mental disorders prevalence in adolescents: A systematic review and meta-analyses. PLoS One. 2020; 15(4): e0232007. Review match

9. Baethge C, Goldbeck-Wood S, Mertens S. SANRA-a scale for the quality assessment of narrative review articles. Res Integr Peer Rev. 2019; 4: 5. Review match

10. Hefti F. Pathogenesis and biomechanics of adolescent idiopathic scoliosis (AIS). J Child Orthop. 2013; 7(1): 17-24. Review match

11. Becker L, Li Z, Wang Z, Pumberger M, Schömig F. Adolescent idiopathic scoliosis is associated with muscle area asymmetries in the lumbar spine. Eur Spine J. 2023; 32(11): 3979-3986. Review match

12. Samaan MC, Missiuna P, Peterson D, Thabane L. Understanding the role of the immune system in adolescent idiopathic scoliosis: Immunometabolic CONnections to Scoliosis (ICONS) study protocol. BMJ Open. 2016; 6(7): e011812. Review match

13. G Bisson D, Lama P, Abduljabbar F, Rosenzweig DH, Saran N, Ouellet JA, Haglund L. Facet joint degeneration in adolescent idiopathic scoliosis. JOR Spine. 2018; 1(2): e1016. Review match

14. Lau KKL, Kwan KYH, Cheung JPY, Wong JSH, Shea GKH, Law KKP, et al. Incidence of back pain from initial presentation to 3 years of follow-up in subjects with untreated adolescent idiopathic scoliosis. Spine Deform. 2024; 12(2): 357-365. Review match

15. An JK, Berman D, Schulz J. Back pain in adolescent idiopathic scoliosis: A comprehensive review. J Child Orthop. 2023; 17(2): 126-140. Review match

16. Wong AYL, Samartzis D, Cheung PWH, Cheung JPY. How Common Is Back Pain and What Biopsychosocial Factors Are Associated With Back Pain in Patients With Adolescent Idiopathic Scoliosis?. Clin Orthop Relat Res. 2019; 477(4): 676-686. Review match

17. Voepel-Lewis T, Caird MS, Tait AR, Malviya S, Farley FA, Li Y, et al. A High Preoperative Pain and Symptom Profile Predicts Worse Pain Outcomes for Children After Spine Fusion Surgery. Anesth Analg. 2017; 124(5): 1594-1602. Review match

18. Yang S, Chang MC. Chronic Pain: Structural and Functional Changes in Brain Structures and Associated Negative Affective States. Int J Mol Sci. 2019; 20(13): 3130. Review match

19. Teles AR, Ocay DD, Bin Shebreen A, Tice A, Saran N, Ouellet JA, et al. Evidence of impaired pain modulation in adolescents with idiopathic scoliosis and chronic back pain. Spine J. 2019; 19(4): 677-686. Review match

20. Raja SN, Carr DB, Cohen M, Finnerup NB, Flor H, Gibson S, et al. The revised International Association for the Study of Pain definition of pain: concepts, challenges, and compromises. Pain. 2020; 161(9): 1976-1982. Review match

21. Ranger TA, Cicuttini FM, Jensen TS, Manniche C, Heritier S, Urquhart DM. Catastrophization, fear of movement, anxiety, and depression are associated with persistent, severe low back pain and disability. Spine J. 2020; 20(6): 857-865. Review match

22. Miller MM, Meints SM, Hirsh AT. Catastrophizing, pain, and functional outcomes for children with chronic pain: a meta-analytic review. Pain. 2018; 159(12): 2442-2460. Review match

23. Ramo BA, Collins-Jones TL, Thornberg D, Klinkerman L, Rathjen K, Jo CH. Pain Catastrophizing Influences Preoperative and Postoperative Patient-Reported Outcomes in Adolescent Idiopathic Scoliosis. J Bone Joint Surg Am. 2022; 104(21): 1859¬1868. Review match

24. Mikkelsen HT, Haraldstad K, Helseth S, Skarstein S, Småstuen MC, Rohde G. Pain and health-related quality of life in adolescents and the mediating role of self-esteem and self-efficacy: a cross-sectional study including adolescents and parents. BMC Psychol. 2021; 9(1): 128. Review match

25. Dai Q, Smith GD. Resilience to depression: Implication for psychological vaccination. Front Psychiatry. 2023; 14: 1071859.

26. Noel M, Groenewald CB, Beals-Erickson SE, Gebert JT, Palermo TM. Chronic pain in adolescence and internalizing mental health disorders: a nationally representative study. Pain. 2016; 157(6): 1333-1338. Review match

27. Tang B, Meng W, Hägg S, Burgess S, Jiang X. Reciprocal interaction between depression and pain: results from a comprehensive bidirectional Mendelian randomization study and functional annotation analysis. Pain. 2022; 163(1): e40-e48. Review match

28. WHO Analgesic Ladder. StatPearls [home page on the Internet]. Anekar AA, Hendrix JM, Cascella M. [updated Apr 23, 2023; cited May 15, 2024]. Accessible at: https://www.ncbi.nlm.nih.gov/books/NBK554435/

29. Hoffman KA, Ponce Terashima J, McCarty D. Opioid use disorder and treatment: challenges and opportunities. BMC Health Serv Res. 2019; 19(1): 884. Review match

30. Tai FWD, McAlindon ME. Non-steroidal anti-inflammatory drugs and the gastrointestinal tract. Clin Med (Lond). 2021; 21(2): 131-134. Review match

31. Amitriptyline. StatPearls [home page on the Internet]. Thour A, Marwaha R; [updated Jul 18, 2023; cited Jan 20, 2024]. Accessible at: https://www.ncbi.nlm.nih.gov/books/NBK537225/

32. Dwyer JB, Bloch MH. Antidepressants for Pediatric Patients. Curr Psychiatr. 2019; 18(9): 26-42F.

33. Arnold LM, Bateman L, Palmer RH, Lin Y. Preliminary experience using milnacipran in patients with juvenile fibromyalgia: lessons from a clinical trial program. Pediatr Rheumatol Online J. 2015; 13:27. Review match

34. Saha K, Torous J, Kiciman E, De Choudhury M. Understanding Side Effects of Antidepressants: Large-scale Longitudinal Study on Social Media Data. JMIR Ment Health. 2021; 8(3): e26589. Review match

35. Rogalski JK, Subdys A, Gawlik-Kotelnicka OE. The development of the Metabolic-associated Fatty Liver Disease during pharmacotherapy of mental disorders - a review. Curr Probl Psychiatry. 2022; 23(3): 128-143. Review match

36. Sturgeon JA. Psychological therapies for the management of chronic pain. Psychol Res Behav Manag. 2014; 7: 115-124.

37. Scott AJ, Webb TL, Martyn-St James M, Rowse G, Weich S. Improving sleep quality leads to better mental health: A meta-analysis of randomised controlled trials. Sleep Med Rev. 2021; 60: 101556. Review match

38. Pandi-Perumal SR, Monti JM, Burman D, Karthikeyan R, BaHammam AS, Spence DW, et al. Clarifying the role of sleep in depression: A narrative review. Psychiatry Res. 2020; 291: 113239. Review match

39. Anastasiades PG, de Vivo L, Bellesi M, Jones MW. Adolescent sleep and the foundations of prefrontal cortical development and dysfunction. Prog Neurobiol. 2022; 218: 102338. Review match

40. Yakut Y, Pelin Z, Yagci G. An investigation of sleep profiles in individuals with idiopathic scoliosis. Sleep Sci. 2022; 15(2): 172¬178. Review match

41. Yang Y, Liu X, Liu ZZ, Tein JY, Jia CX. Life stress, insomnia, and anxiety/depressive symptoms in adolescents: A three-wave longitudinal study. J Affect Disord. 2023; 322: 91-98. Review match

42. Wang Y, Wang D, Zhang G, Ma B, Ma Y, Yang Y, et al. Effects of spinal deformities on lung development in children: a review. J Orthop Surg Res. 2023; 18(1): 246. Review match

43. McPhail GL, Ehsan Z, Howells SA, Boesch RP, Fenchel MC, Szczesniak R, et al. Obstructive Lung Disease in Children with Idiopathic Scoliosis. J Pediatr. 2015; 166(4): 1018–1021. Review match

44. Qiabi M, Chagnon K, Beaupré A, Hercun J, Rakovich G. Scoliosis and bronchial obstruction. Can Respir J. 2015; 22(4): 206-208. Review match

45. Borges-Santos E, Wada JT, da Silva CM, Silva RA, Stelmach R, Carvalho CR, et al. Anxiety and depression are related to dyspnea and clinical control but not with thoracoabdominal mechanics in patients with COPD. Respir Physiol Neurobiol. 2015; 210: 1-6. Review match

46. Li X, Guo H, Chen C, Tan H, Lin Y, Li Z, et al. Does Scoliosis Affect Sleep Breathing?. World Neurosurg. 2018; 118: e946-e950. Review match

47. Edwards C, Almeida OP, Ford AH. Obstructive sleep apnea and depression: A systematic review and meta-analysis. Maturitas. 2020; 142: 45-54. Review match

48. Gao H, Han Z, Huang S, Bai R, Ge X, Chen F, et al. Intermittent hypoxia caused cognitive dysfunction relate to miRNAs dysregulation in hippocampus. Behav Brain Res. 2017; 335: 80¬87. Review match

49. Kowiański P, Lietzau G, Czuba E, Waśkow M, Steliga A, Moryś J. BDNF: A Key Factor with Multipotent Impact on Brain Signaling and Synaptic Plasticity. Cell Mol Neurobiol. 2018; 38(3): 579¬593. Review match

50. Devita M, Montemurro S, Ramponi S, Marvisi M, Villani D, Raimondi MC, et al. Obstructive sleep apnea and its controversial effects on cognition. J Clin Exp Neuropsychol. 2017; 39(7): 659¬669. Review match

51. Kan MMP, Negrini S, Di Felice F, Cheung JPY, Donzelli S, Zaina F, et al. Is impaired lung function related to spinal deformities in patients with adolescent idiopathic scoliosis? A systematic review and meta-analysis-SOSORT 2019 award paper. Eur Spine J. 2023; 32(1): 118-139. Review match

52. Obbarius N, Fischer F, Liegl G, Obbarius A, Rose M. A Modified Version of the Transactional Stress Concept According to Lazarus and Folkman Was Confirmed in a Psychosomatic Inpatient Sample. Front Psychol. 2021; 12: 584333. Review match

53. Russo K. Assessment and Treatment of Adolescents With Chronic Medical Conditions. J Health Serv Psychol. 2022; 48(2): 69-78. Review match

54. Orzechowska A, Maruszewska P, Gałecka M, Hyland P, Boduszek D, Gałecki P, et al. Emotional control in selected somatic and psychiatric diseases. BMC Psychiatry. 2023; 23(1): 802. Review match

55. Rogalski JK, Makowska IE, Wȩglewska K, Płeska K. Samouszkodzenia bez intencji samobójczej i zaburzenia odżywiania — rola regulacji emocjonalnej. Psychiatria. 2022; 19(4): 292-298. Review match

56. Demichelis OP, Grainger SA, Hubbard RE, Henry JD. Emotion regulation mediates the relationship between social frailty and stress, anxiety, and depression. Sci Rep. 2023; 13(1): 6430. Review match

57. Lacomba-Trejo L, Valero-Moreno S, Montoya-Castilla I, Pérez-Marín M. Psychosocial Factors and Chronic Illness as Predictors for Anxiety and Depression in Adolescence. Front Psychol. 2020; 11: 568941. Review match

58. Body Image Distortion. StatPearls [home page on the Internet]. Hosseini SA, Padhy RK; [updated Sep 4, 2023; cited Feb 3, 2024]; Accessible at: https://www.ncbi.nlm.nih.gov/books/ NBK546582/

59. Wichstrøm L, von Soest T. Reciprocal relations between body satisfaction and self-esteem: A large 13-year prospective study of adolescents. J Adolesc. 2016; 47: 16-27. Review match

60. Bertuccelli M, Cantele F, Masiero S. Body Image and Body Schema in Adolescents with Idiopathic Scoliosis: A Scoping Review. Adolesc Res Rev. 2023; 8(1): 97-115. Review match

61. Korovessis P, Zacharatos S, Koureas G, Megas P. Comparative multifactorial analysis of the effects of idiopathic adolescent scoliosis and Scheuermann kyphosis on the self-perceived health status of adolescents treated with brace. Eur Spine J. 2007; 16(4): 537-546. Review match

62. Lin T, Meng Y, Ji Z, Jiang H, Shao W, Gao R, et al. Extent of Depression in Juvenile and Adolescent Patients with Idiopathic Scoliosis During Treatment with Braces. World Neurosurg. 2019; 126: e27-e32. Review match

63. Carrasco MIB, Ruiz MCS. Perceived self-image in adolescent idiopathic scoliosis: an integrative review of the literature. Rev da Esc Enferm da USP. 2014; 48(4): 748-757. Review match

64. Kaya MH, Erbahçeci F, Alkan H, Kocaman H, Büyükturan B, Canlı M, et al. Factors influencing of quality of life in adolescent idiopathic scoliosis. Musculoskelet Sci Pract. 2022; 62: 102628. Review match

65. Auerbach JD, Lonner BS, Crerand CE, Shah SA, Flynn JM, Bastrom T, et al. Body image in patients with adolescent idiopathic scoliosis: validation of the Body Image Disturbance Questionnaire--Scoliosis Version. J Bone Joint Surg Am. 2014; 96(8): e61. Review match

66. Lonner BS, Brochin R, Lewis R, Vig KS, Kassin G, Castillo A, et al. Body Image Disturbance Improvement After Operative Correction of Adolescent Idiopathic Scoliosis. Spine Deform. 2019; 7(5): 741-745. Review match

67. Çolak TK, Akgül T, Çolak I, Dereli EE, Chodza M, Dikici F. Health related quality of life and perception of deformity in patients with adolescent idiopathic scoliosis. J Back Musculoskelet Rehabil. 2017; 30(3): 597-602. Review match

68. Adedeji A, Otto C, Kaman A, Reiss F, Devine J, Ravens-Sieberer U. Peer Relationships and Depressive Symptoms Among Adolescents: Results From the German BELLA Study. Front Psychol. 2022; 12: 767922. Review match

69. Raboteg-Saric Z, Sakic M. Relations of Parenting Styles and Friendship Quality to Self-Esteem, Life Satisfaction and Happiness in Adolescents. Appl Res Qual Life. 2014; 9(3): 749¬765. Review match

70. Chiu K, Clark DM, Leigh E. Prospective associations between peer functioning and social anxiety in adolescents: A systematic review and meta-analysis. J Affect Disord. 2021; 279: 650-661. Review match

71. D'Agata E, Sánchez-Raya J, Bagó J. Introversion, the prevalent trait of adolescents with idiopathic scoliosis: an observational study. Scoliosis Spinal Disord. 2017;12: 27. Review match

72. Piantoni L, Tello CA, Remondino RG, Bersusky ES, Menéndez C, Ponce C, et al. Quality of life and patient satisfaction in bracing treatment of adolescent idiopathic scoliosis. Scoliosis Spinal Disord. 2018; 13: 26. Review match

73. Glowacki M, Misterska E, Adamczyk K, Latuszewska J. Changes in Scoliosis Patient and Parental Assessment of Mental Health in the Course of Cheneau Brace Treatment Based on the Strengths and Difficulties Questionnaire. J Dev Phys Disabil. 2013; 25(3): 325-342. Review match

74. Marinov D, Valtcheva E. A case-control study on physical activity of teenagers with adolescent idiopathic scoliosis. Eur J Public Health. 2021;31 (Supplement_3). Review match

75. Glavaš J, Rumboldt M, Karin Ž, Matković R, Bilić-Kirin V, Buljan V, et al. The Impact of Physical Activity on Adolescent Idiopathic Scoliosis. Life (Basel). 2023; 13(5): 1180. Review match

76. Vancampfort D, Stubbs B, Firth J, Van Damme T, Koyanagi A. Sedentary behavior and depressive symptoms among 67,077 adolescents aged 12-15 years from 30 low- and middle-income countries. Int J Behav Nutr Phys Act. 2018; 15(1): 73. Review match

77. Silva LRB, Seguro CS, de Oliveira CGA, Santos POS, de Oliveira JCM, de Souza Filho LFM, et al. Physical Inactivity Is Associated With Increased Levels of Anxiety, Depression, and Stress in Brazilians During the COVID-19 Pandemic: A Cross-Sectional Study. Front Psychiatry. 2020; 11: 565291. Review match

78. Schuch FB, Vancampfort D, Richards J, Rosenbaum S, Ward PB, Stubbs B. Exercise as a treatment for depression: A meta-analysis adjusting for publication bias. J Psychiatr Res. 2016; 77:42-51. Review match

79. Verhoeven JE, Han LKM, Lever-van Milligen BA, Hu MX, Révész D, Hoogendoorn AW, et al. Antidepressants or running therapy: Comparing effects on mental and physical health in patients with depression and anxiety disorders. J Affect Disord. 2023; 329: 19-29. Review match

80. Nguyen Ho PT, Ha PBT, Tong T, Bramer WM, Hofman A, Lubans DR, et al. Mechanisms Linking Physical Activity with Psychiatric Symptoms Across the Lifespan: A Systematic Review. Sports Med. 2023; 53(11): 2171-2190. Review match

81. Yagci G, Yakut Y. Core stabilization exercises versus scoliosis-specific exercises in moderate idiopathic scoliosis treatment. Prosthet Orthot Int. 2019; 43(3): 301-308. Review match

82. Seleviciene V, Cesnaviciute A, Strukcinskiene B, Marcinowicz L, Strazdiene N, Genowska A. Physiotherapeutic Scoliosis-Specific Exercise Methodologies Used for Conservative Treatment of Adolescent Idiopathic Scoliosis, and Their Effectiveness: An Extended Literature Review of Current Research and Practice. Int J Environ Res Public Health. 2022; 19(15): 9240. Review match

83. Ma K, Wang C, Huang Y, Wang Y, Li D, He G. The effects of physiotherapeutic scoliosis-specific exercise on idiopathic scoliosis in children and adolescents: a systematic review and meta-analysis. Physiotherapy. 2023; 121: 46-57. Review match

84. Li X, Shen J, Liang J, Zhou X, Yang Y, Wang D, et al. Effect of core-based exercise in people with scoliosis: A systematic review and meta-analysis. Clin Rehabil. 2021; 35(5): 669-680. Review match

85. Law D, Cheung MC, Yip J, Yick KL, Wong C. Scoliosis brace design: influence of visual aesthetics on user acceptance and compliance. Ergonomics. 2017; 60(6): 876-886. Review match

86. Zimoń M, Matusik E, Kapustka B, Durmala J, Doroniewicz I, Wnuk B. Conservative management strategies and stress level in children and adolescents with idiopathic scoliosis. Psychiatr Pol. 2018; 52(2): 355-369. Review match

87. Pinto A, Faiz O, Davis R, Almoudaris A, Vincent C. Surgical complications and their impact on patients' psychosocial well¬being: a systematic review and meta-analysis. BMJ Open. 2016; 6(2): e007224. Review match

88. Akortiakuma MJK, Dzansi DG, Aziato PL. Psychological well¬being of patients recovering from abdominal surgery: A qualitative study. Perioper Care Oper Room Manag. 2022; 26: 100228. Review match

89. Duramaz A, Yılmaz S, Ziroğlu N, Bursal Duramaz B, Kara T. The effect of deformity correction on psychiatric condition of the adolescent with adolescent idiopathic scoliosis. Eur Spine J. 2018; 27(9): 2233-2240.

Downloads

Published

2025-01-09