Comparison of classic and modern methods of furocoumarinsextraction from Angelica officinalis Hoffm. and Pastinaca sativa L. fruits
Abstract
Simple extraction methods as macetarion, shaking, extraction, sonication-assistrd extraction (80%, 100%), homogenisation followed by sonication-assisted extraction were used to obtain coumarins from A. officinalis and P. sativa. The yield of coumarin extracted was compared by means of TLC and densitometry. The best results were obtained by means of modified ultrasound-assisted extraction: 1.8094 mg/g of xanthotoxin and 3.3109 mg/g sum of bergapten and imperatorin in Pastinaca sativa fruits and 2.2511 mg/g of xanthotoxin and 25.0069 mg/g sum of bergapten and imperatorin in Archangelica officinalis fruits.
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