The influence of starch hydrolysates on rheological properties of mucilage solutions and the ability of tablets for water sorption

Authors

  • Piotr Belniak Chair and Department of Applied Pharmacy, Medical University of Lublin Author
  • Dariusz Matosiuk Chair and Department of Synthesis and Chemical Technology of Pharmaceutical Substances, Medical University of Lublin Author
  • Wiktor Czarnecki Chair and Department of Applied Pharmacy, Medical University of Lublin Author

DOI:

https://doi.org/10.12923/

Abstract

The purpose of this study was to investigate the influence of starch hydrolysates on the dynamic viscosity of mucilage solutions and on the ability of water sorption of tablets with the above hydrolysates. Aqueous mucilage solutions at different concentrations ranging from 1 to 10 % (w/v) were prepared. The obtained mucilage solutions were examined for density and viscosity.

Tablets with the weight of 83.62–104.30 mg, having hardness ranging from 0.21 to 0.59 kg/mm2, absolute density from 0.98 to 1.18 g/cm3, were pressed on a single punch eccentric tabletting machine (Korch EK0, Berlin, Germany). Tablets were tested for water sorption using the climatic test chamber (Wamed KBK-65W, Poland).

References

1. Brulage H. M., Lee C. O., Rising L. H.: Physical and technical pharmacy. The McGraw-Hill Book Company Inc., 489, New York 1963.

2. Funami T. et al.: Food hydrocolloids control the gelatinization and retrogradation behavior of starch. Functions of guar gums with different molecular weights on the gelatinization behavior of corn starch. Food Hydrocolloids, 19, 15, 2005.

3. Koocheki A. et al.: Rheological properties of mucilage extracted from Alyssum homolocarpum seed as a new source of thickening agent. J. Food Engineering, 91, 490, 2009.

4. Krzyżaniak W. et al.: Charakterystyka chemiczna maltodekstryn o małym równoważniku glukozowym otrzymanych przez hydrolizę skrobi ziemniaczanej za pomocą alfa-amylaz. Technol, Aliment., 2(2), 5, 2003.

5. Nagano T., Tamaki E., Funami T.: Influence of guar gum on granule morphologies and rheological properties of maize starch. Carbohydrate Polymers, 72, 95, 2008.

6. Polish Pharmacopeia 7th edition, Warsaw 2006.

7. Tuovinen L., Peltonen S., Jarvinen K.: Drug release from starch – acetate films. Journal of Controlled Release, 91, 345, 2003.

Annales Sectio DDD, XXIII, 1

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Published

2025-04-04

Issue

Vol. 23 No. 1 (2010): Annales UMCS, Pharmacia, Sectio DDD, Volume XXIII

Section

Artykuły

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