The fresh extracts of Allium species as potential in vitro agents against planktonic and adherent cells of Candida spp.
DOI:
https://doi.org/10.12923/Abstract
The aim of this paper was to compare the activity of fresh water extract of Allium sativum, Allium ursinum, Allium victorialis, Allium scorodoprasum against planktonic cells
of Candida spp. (C. albicans, C. famata, C. glabrata, C. krusei) and those attached to the catheters in relation to cytotoxicity of the plant extracts to green monkey kidney (GMK) cells. The extracts of Allium plants, besides Allium scorodoprasum, inhibited growth of planktonic cells of Candida spp. at the concentrations ranging from 0.5 to 4.0 mg/ml, while that of adherent cells – at the concentrations ranging from 1.0 to > 4.0 mg/ml, depending on the yeast and plant species. The most effective was the extract of Allium sativum. Extracts of Allium plants exerted only a slight inhibitory effect on GMK cells even at the concentration of 4.0 mg/ml.
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