The influence of long-term treatment with monosodium glutamate on pancreas in rats

Authors

  • YA. Savytskyy Danylo Halytskyi Lviv National Medical University Author
  • T. Falalyeyeva Taras Shevchenko National University of Kyiv Author

DOI:

https://doi.org/10.12923/

Keywords:

monosodium glutamate, pancreas, pancreatitis

Abstract

The effects of long-term injection of food additive monosodium glutamate (MG) on pancreatic tissue in 30 white rats was investigated. It was established that during 30 days of daily MG injection in the doses 15 and 30 mg/kg the cross-sectional area of nuclei of endocrine cells, the cross-sectional area of nuclei of exocrine pancreatic cells, the distance between lobules of the pancreas were increased but the cross-sectional area of the exocrine pancreatic cells was decreased. Thus histological evaluation of pancreatic tissue of rats in 30 days of MG injection indicates that pancreatitis is developed.

References

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Published

2025-04-09

Issue

Vol. 23 No. 2 (2010): Annales UMCS, Pharmacia, Sectio DDD, Volume XXIII

Section

Artykuły

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