Acute complications of diabetes – the present state of knowledge. Part I. Diabetic ketoacidosis

Authors

  • Andrzej Nowakowski Department of Endocrinology, Medical University, Lublin Author
  • Beata Matuszek Department of Endocrinology, Medical University, Lublin Author

DOI:

https://doi.org/10.12923/

Keywords:

diabetic ketoacidosis, type 1 diabetes, type 2 diabetes, epidemiology, pathogenesis, clinical picture, standards of treatment

Abstract

Diabetic ketoacidosis (DKA) is the most common acute hyperglycemic complication, which poses problems mostly in type 1 diabetes, sporadically in type 2. The most frequent cause of developing ketoacidosis in patients with type 1 diabetes is withdrawal of or missing an insulin dose or delayed diagnosis; in patients with type 2 diabetes it is severe infection or stress with accompanying relative insulin deficiency. The basis for diagnosis is hyperglycemia, ketonemia and/or ketonuria and features of metabolic acidosis. Mortality in the pathology reaches 5%. The study presents the current state of knowledge about DKA concerning epidemiology, pathogenesis, clinical picture and particularly current standards of treatment.

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Published

2010-09-30

Issue

Vol. 23 No. 3 (2010): Annales UMCS, Pharmacia, Sectio DDD, Volume XXIII

Section

Artykuły

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