Acute complications of diabetes – the present state of knowledge. Part II. Non-ketotic hyperosmolar hyperglycemia

Authors

Keywords:

non-ketotic hyperosmolar hyperglycemia, type 2 diabetes, epidemiology, pathogenesis, treatment directives

Abstract

Non-ketotic hyperosmolar hyperglycemia (NKHH) is, besides diabetic ketoacidosis, a second most serious acute complication of diabetes. It occurs mainly in  patients with type 2 diabetes, particularly in elderly people who are unable to maintain adequate fluid intake or have partial renal insufficiency. It is characterized by severe hyperglycemia, hyperosmolarity and dehydration in the absence of ketosis. It carries a 15% mortality risk. The aim of this study is to present the current state of knowledge about NKHH including epidemiology, pathogenesis, clinical features and treatment directives.

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Published

2010-12-30

Issue

Vol. 23 No. 4 (2010): Annales UMCS, Pharmacia, Sectio DDD, Volume XXIII

Section

Artykuły

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