The influence of long-term treatment with monosodium glutamate on gastric mucosa in rats
Keywords:
monosodium glutamate, gastric mucosa, water immersion restraint stressAbstract
In acute experiments on 42 white rats we showed that the injection of monosodium glutamate (MG) during 30 days to rats in doses 15 and 30 mg/kg (1 and 2 gram of MG on average statistical person) evoked gastric mucosa (GM) lesions (ulcers, erosions and hemorrhages) and strengthened the stress action on GM. We concluded that the long-term excessive consumption of MG can lead to gastritis and ulcer disease of stomach. Secondly, the maximum daily dose of MG, as well as other food additives must be reviewed with regard to their effect on GM.
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