Some aspects of the use of herbs in the treatment of conjunctivitis

Authors

  • Anna Matysik-Woźniak Klinika Okulistyki Uniwersytetu Medycznego w Lublinie Author
  • Elżbieta Matysik Samodzielna Pracownia Chromatografii Planarnej Uniwersytetu Medycznego w Lublinie Author
  • Elżbieta Weryszko-Chmielwska Katedra Botaniki, Uniwersytet Przyrodniczy w Lublinie Author
  • Roman Paduch Zakład Wirusologii i Immunologii, Instytut Mikrobiologii i Biotechnologii UMCS w Lublinie Author

Keywords:

herbs, conjunctivitis, antibiotic resistance, eye drops

Abstract

Herbal preparations are presently enjoying a higher degree of confidence among patients both in the developed and developing world. For ages such preparations have been employed in the treatment of conjunctivitis and inflammation of eyelids due to the antibacterial, antiviral and antifungal properties of their various components.
Infusions prepared from some plants are believed to act as antiallergens, anticongestants, antiinflammators; hence the treatment of ocular disease conditions may turn out to be more complex.
The spreading condition of antibiotic resistance of bacteria makes it necessary to search for new antimicrobic substances. It seems that some herbs may act as supplementary in antibiotic therapy in ophthalmology, and in some cases they may curtail the use of antibiotics.
 The choice of the herbal preparation is of vital importance, as well as its standardization based on scientific research on, among other methods, cell lines and animals. This allows for elimination of components that have toxic or allergenic properties. The present paper deals in detail with plantain (Plantago lanceolata L.) and eyebright (Euphrasia officinalis L.) considering their application in ophthalmology.

References

1. Revoltella RP, Papini A. Epithelial stem cells of the eye surface. Cell Prolif 2007;40:445-61.

2. Zagórski Z, Naumann GOH, Watson P. Choroby rogówki, twardówki i powierzchni oka. Lublin: Wydawnictwo Czelej; 2008, s. 168-70.

3. Rios JL, Recio MC. Medicinal plants and antimicrobial activity. J Ethnopharmacol 2005;100:80-4.

4. Foster A, Johnson GG. Traditional eye medicines-good or bad news? Br J Ophthalmol 1994;78(11):807.

5. Sharma P, Singh G. A review of plant species used to treat conjunctivitis. Review article. Phytother Res 2002;16:1-22.

6. Czapska A, Bałasińska B, Szczawiński J. Działanie przeciwbakteryjne i przeciwdrobnoustrojowe ekstraktów przypraw żywnościowych. Medycyna Wet 2006;62(3):302-5.

7. Biswas NR, Gupta SK, Das GK, Kumar N, Mongre PK, Halfar D, Beri S. Evaluation of Ophthacare eye drops – a herbal formulation in the management of various ophthalmic disorders. Phytother Res 2001;15:618-20.

8. Samuelsen AB. The traditional uses, chemical constituents and biological activities of Plantago major L. A review. J Ethnopharmacol 2000;71(1-2):1-21.

9. Recio MC, Giner MR, Manez S, Rios JL. Structural considerations on the iridoids as anti-inflammatory agents. Planta Med 1994;60:232-4.

10. Park KS, Chang IM. Anti-inflammatory activity of aucubin by inhibition of tumor necrosis factor-α production in RAW 264.7 cells. Planta Med 2004;70:778-9.

11. Jeong HJ, Koo HN, Na HJ, Kim MS, Hong SH, Eom JW, Kim KKS, Shin TY, Kim HM. Inhibition of TNF-α and IL-6 production by aucubin through blockade of NF-κB activation in RBL-2H3 mast cells. Cytokine 2002;18:252-9.

12. Shim KM, Choi SH, Jeong MJ, Kang SS. Effects of aucubin on the healing wounds. In vivo 2007;21:1037-41.

13. Yuan CS, Zhang Q, Xie WD, Yang XP, Jia ZJ. Iridoids from Pedicularis kansuensis forma albiflora. Pharmazie 2003;58(6):428-30.

14. An SJ, Pae HO, Oh GS, Choi BM, Jeong S, Jang SI Oh H, Kwon TO, Song CE Chung HT. Inhibition of TNF-α, IL-1 β and IL-6 productions and NF-κВ activation in lipopolysaccharide-activated RAW 264.7 macrophages by catalposide, an iridoid glycoside isolated from Catalpa ovata G. Don (Bignoniaceae). Int Immunopharmacol 2002;2:1173-81.

15. Park BG, Lee HS, Jung SH, Hong CO, Won HJ, Park HY, Ryu YS, Lee SJ, Kim KH, Park KW, Lee KW. A 90 day repeated oral toxicity study on plantamajoside concentrate from Plantago asiatica. Phytother Res 2007;21:1118-23.

16. Chiang LC, Chiang W, Chang MY, Ng LT, Lin CC. Antiviral activity of Plantago major extracts and related compounds in vitro. Antiviral Res 2002;55:53-62.

17. Chiang LC, Chiang W, Chang MY, Lin CC. In vitro cytotoxic, antiviral and immunomodulatory effects of Plantago major and Plantago asiatica. Am J Chin Med 2003;31(2):225-34.

18. Beara IN, Lesiak MM, Jogin ED, Balog KJ, Anackov GT, Orcic DZ, Mimica-Dukic NM. Plantain (Plantago L.) species as novel sources of flavonoid antioxidants. J Agric Ford Chem 2009;57:9268-73.

19.Chiang LC, Ng LT, Chiang W, Chang MY, Lin CC. Immunomodulatory activities of flavonoids, monoterpenoids, triterpenoids, iridoid glycosides and phenolic compounds of Plantago species. Planta Med 2003;69(7):600-4.

20. Galvez M, Martin-Cordreo C, Houghton PJ, Ayuso MJ. Antioxidant activity of Plantago bellardi. All Phytother Res 2005; 19:1074-6.

21.Rezaeipoor R, Saeidnia S, Kamalinejad M. The effect of Plantago ovata on humoral immune response in experimental animals. J Ethnopharmacol 2000;72:283-6.

22. Gonzalez MG, Morale TC, Soto Rodriguez GA, Pazos L. Toxicidad sub-cronica y prueba de irritabiliad ocular del extracto acuoso de las hojas de Plantago major (Plantaginaceae). Rev Biol Trop 2003;51:635-8.

23. Kozłowski J, Krajewska A. Ziele świetlika (Herba Euphrasiae) jako surowiec roślinny. Farm Pol 1982;38(10):471-4.

24. Hojden B. Świetlik łąkowy-ulga dla oczu. Wiad Ziel 2000;42:7-8.

25. Stoss M, Michels C, Peter E, Beutke R, Gorter RW. Prospective cohort trial of Euphrasia single-dose eye drops in conjunctivitis. J Altern Complement Med 2000;6:499-508.

26. Trovato A, Monforte MT, Rossitto A, Forestieri AM. In vitro cytotoxic effect of some medicinal plants containing flavonoids. Boll Chim Farm 1996;135(4):263-6.

27. West AL., Fetters MD, Hemmila MR, Gorenflo DW, Kiyota A, Moroi-Fetters S. Herb and vitamin supplementation use among a general ophthalmology practice population. Am J Ophthalmol 2005;139:522-9.

28. Barrero AF, Oltra JE, Alvarez M, Raslan DS, Saute DA, Akssira M. New sources and antifungal activity of sesquiterpene lactones. Fitoterapia 2000;71:60-4.

29. Bielory L, Heimall J. Rewiev of complementary and alternative medicine in treatment of ocular allergies. Curr Opin Allergy Clin Immunol 2003;3,395-9.

Downloads

Published

2011-01-01